In bowl, whisk together flour, Pumpkin Pie Spice, baking soda, baking powder, cinnamon and salt.
In large bowl, whisk together granulated sugar, brown sugar and eggs until light and smooth. Whisk in pumpkin purée, oil and vanilla until combined. Scrape into prepared pan, smoothing top. Sprinkle with crumble, gently pressing it in.
Bake until loaf is golden and cake tester inserted in centre comes out clean, covering with foil if top is browning too quickly, 65 to 75 minutes. Let cool on rack for 10 minutes; then remove from pan, remove parchment and let cool on rack.